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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.22, no.5, 2009³â, pp.425-430
¿À·¹°¡³ë(Origanum majorana L.) ÃßÃâ¹°ÀÇ Ç×»êÈ­ È¿°ú
( The Antioxidative Effects of Oregano (Origanum majorana L.) Extracts )
ÀÓÅÂÁø;ÃÖ¹«¿µ; »óÁö´ëÇб³ »ý¸í°øÇаú;»óÁö´ëÇб³ ½Äǰ¿µ¾çÇаú;
 
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º» ¿¬±¸ÀÇ ¸ñÀûÀº ¿À·¹°¡³ë ÃßÃâ¹°ÀÇ À¯¸® ¶óµðÄ® ¼Ò°Å ¹× ÁöÁú°ú»êÈ­ ¾ïÁ¦ µî Ç×»êÈ­ È¿°ú¸¦ Á¶»çÇϱâ À§ÇÔÀÌ´Ù. PyrogallolÀÇ ¾ïÁ¦À²À» 100%·Î ±âÁØÇÏ¿´À» ¶§, DPPH ¶óµðÄ®À» 50% ¾ïÁ¦½Ã۴µ¥ ÇÊ¿äÇÑ ¿À·¹°¡³ë ÇÔ·®Àº $21.8{mu}g$À̾ú´Ù. ÃÑÇ×»êÈ­ Ȱ¼ºÀº °­·ÂÇÑ ÀÚÀ¯¶óµðÄ®¿¡ ´ëÇÑ ÃÑÇ×»êÈ­´ÉÀ¸·Î ÃøÁ¤ÇÏ¿´´Ù. ¿À·¹°¡³ë ÃßÃâ¹° 7.5 ¹× $15{mu}g$ÀÇ ÃÑÇ×»êÈ­´ÉÀº °¢°¢ 15.1 ¹× 31.4 nmol Trolox¿Í ´ëµîÇÑ ¼öÁØÀ̾ú´Ù. ¿À·¹°¡³ë ÃßÃâ¹° 0.2 ¹× $0.4{mu}g$ÀÇ »ê¼Ò¶óµðÄ® ¼Ò°Å´ÉÀº °¢°¢ 1.4 ¹× 2.4 nmol gallic acid¿Í ´ëµîÇÑ ¼öÁØÀ̾ú´Ù. ¿À·¹°¡³ë ÃßÃâ¹° 30 ¹× $75{mu}g$ÀÇ ÃÑÆä³î ÇÔ·®Àº °¢°¢ 40.5 ¹× 83.9 nmol gallic acid¿Í ´ëµîÇÑ ¼öÁØÀ̾ú´Ù. ÁöÁú°ú»êÈ­¿¡ ´ëÇÑ ¾ïÁ¦È¿°ú´Â ÀÌȲȭö/¾Æ½ºÄÚ¸£ºó»ê¿¡ ÀÇÇØ À¯µµµÈ ·§µå °£ ¹ÌÅäÄܵ帮¾Æ¸¦ ÀÌ¿ëÇÏ¿© Á¶»çÇÏ¿´´Ù. ¿À·¹°¡³ë ÃßÃâ¹° 20 ¹× $50{mu}g$Àº TBARS ¼öÁØÀ» °¢°¢ 20 ¹× 64% ¾ïÁ¦½ÃÄ×´Ù. À̿Ͱ°ÀÌ ¿À·¹°¡³ë ÃßÃâ¹°ÀÇ °­·ÂÇÑ Ç×»êÈ­ È¿°ú´Â Àû¾îµµ ÀÚÀ¯¶óµðÄ®ÀÇ »êÈ­¾ïÁ¦¿Í ÁöÁú°ú»êÈ­ ¾ïÁ¦¿¡ ±âÀÎÇÏ´Â °ÍÀ¸·Î »ç·áµÈ´Ù.
The objective of this study was to investigate the antioxidative capacity of oregano extracts. Amount of oregano extract at which DPPH radical scavenging activity was inhibited by 50% was $21.8{mu}g$ as compared to 100% by pyrogallol as a reference. Total antioxidant status was examined by total antioxidant capacity against potent free radical reactions. Total antioxidant capacities of oregano extract at the amounts of 7.5 and $15{mu}g$ were 15.1 and 31.4 nmol Trolox equivalents, respectively. Oxygen radical absorbance capacities of oregano extract at the amounts of 0.2 and $0.4{mu}g$ were 1.4 and 2.4 nmol gallic acid equivalents, respectively. Total phenolic contents of oregano extract at the amounts of 30 and $75{mu}g$ were 40.5 and 83.9 nmol gallic acid equivalents, respectively. The inhibitory effect of oregano extract on lipid peroxidation was examined using rat liver mitochondria induced by $FeSO_4$/ascorbic acid. Oregano extracts at the amounts of 20 and $50{mu}g$ decreased TBARS level by 20 and 64%, respectively. Thus strong antioxidant effects of oregano extract seem to be due to, at least in part, the prevention against free radicals-induced oxidation, followed by inhibition of lipid peroxidation.
 
Ű¿öµå
Oregano;Radical;Antioxidant;Lipid peroxidation;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.22, no.5, 2009³â, pp.425-430
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200934939665744)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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