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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.22, no.2, 2009³â, pp.145-151
»ó¹éÇÇ ÃßÃâ¹°ÀÇ Ç×»êÈ­ Ȱ¼º ¹× ¹Ì¹éÈ¿°ú
( Antioxidant Activities and Whitening Effect of the Mulberry (Morus alba L.) Root Bark Extracts )
Áö¼±¿Á; ÁߺδëÇб³ È­Àåǰ°úÇаú;
 
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º» ¿¬±¸´Â »ó¹éÇÇ ÃßÃâ¹°ÀÇ È­Àåǰ ¾à¸®È°¼ºÀÎ Ç×»êÈ­ Ȱ¼º°ú ¹Ì¹é È¿°ú¸¦ Ž»öÇϱâ À§ÇØ ¿­¼öÃßÃâ¹°°ú ¿¡Åº¿ÃÃßÃâ¹°À» »ç¿ëÇÏ¿© ÀüÀÚ°ø¿©´É, ABTS, xanthine oxidase ÀúÇØÈ°¼º, nitric oxide radical ¼Ò°Å´É ¹× tyrosinase ÀúÇØ Ȱ¼ºÀ» ÃøÁ¤ÇÏ¿´´Ù. »ó¹éÇÇ ÃßÃâ¹°ÀÇ ÀüÀÚ°ø¿©´É ÃøÁ¤°á°ú $1,000;{mu}g/ml$¿¡¼­ ¿­¼öÃßÃâ¹°Àº 65.8%, ¿¡Åº¿ÃÃßÃâ¹°Àº 87%ÀÇ DPPH radical ¼Ò°Å´ÉÀ» º¸¿´´Ù. ABTS ¶óµðÄ® ¼Ò°Å´ÉÀº $1,000;{mu}g/ml$¿¡¼­ ¿­¼öÃßÃâ¹°Àº 89.3%, ¿¡Åº¿ÃÃßÃâ¹°Àº 77.1%·Î ³ôÀº ¼Ò°Å´ÉÀ» º¸¿´´Ù. Xanthine oxide ÀúÇØÈ°¼ºÀº $1,000;{mu}g/ml$¿¡¼­ ¿­¼öÃßÃâ¹°Àº 100%, ¿¡Åº¿ÃÃßÃâ¹°Àº 96.2%¸¦ º¸¿© ³ôÀº Ç×»êÈ­ È¿°ú¸¦ ³ªÅ¸³»¾ú´Ù. NO ¼Ò°Å´ÉÀº $500;{mu}g/ml$¿¡¼­ ¿­¼öÃßÃâ¹°Àº 43.5%, ¿¡Åº¿ÃÃßÃâ¹°Àº 53%¸¦ ³ªÅ¸³»¾ú´Âµ¥ ÀÌ´Â °°Àº ³óµµ¿¡¼­ ´ëÁ¶±¸ÀÎ BHAÀÇ 43.8%¿Í À¯»çÇÏ¿´´Ù. Tyrosinase ÀúÇØÈ°¼ºÀº $1,000;{mu}g/ml$¿¡¼­ ¿­¼öÃßÃâ¹°Àº 79.6%, ¿¡Åº¿ÃÃßÃâ¹°Àº 93.5%·Î ³ªÅ¸³ª ´ëÁ¶±¸ÀÎ ºñŸ¹Î C¿Í À¯»çÇÑ È°¼ºÀ» º¸¿© ¹Ì¹éÈ¿°ú°¡ ¿ì¼öÇÏ¿´´Ù. ¸ðµç ½ÇÇè¿¡¼­ Ȱ¼ºÁ¤µµ°¡ ½Ã·á ³óµµ°¡ Áõ°¡ÇÔ¿¡ µû¶ó À¯ÀÇÀûÀ¸·Î Áõ°¡ÇÏ´Â °æÇâÀ̾úÀ¸¸ç, ABTS ÀúÇØÈ°¼ºÀ» Á¦¿ÜÇÏ°í ´ëºÎºÐÀÇ ½ÇÇè¿¡¼­ ¿¡Åº¿ÃÃßÃâ¹°ÀÌ ¿­¼öÃßÃâ¹°¿¡ ºñÇØ ´Ù¼Ò ³ôÀº Ȱ¼ºÀ» º¸¿´´Ù.
This study was performed to investigate the antioxidant activities and the whitening effect of mulberry (Morus alba L.) root bark extracts. The antioxidant activities of water and 70% ethanol extracts of mulberry root bark were 65.8% and 87.0% in the DPPH assay at $1,000;{mu}g/ml$ ; 89.3% and 77.1% in the ABTS assay at $1,000;{mu}g/ml$. Xanthine oxidase inhibition of water and 70% ethanol extracts were 100% and 96.2% at $1,000;{mu}g/ml$. Nitric oxide radical inhibition of water and 70% ethanol extracts showed 43.5% and 53.0% at $500;{mu}g/ml$, and it was similar to the BHA effect(43.8%). Tyrosinase inhibitory activities of water and 70% ethanol extracts were 79.6% and 93.5% at $1,000;{mu}g/ml$. These results confirm that mulberry root bark has the great potential to be a cosmeceutical ingredient with a natural antioxidant and a skin-whitening effect.
 
Ű¿öµå
Morus alba L. DPPH;ABTS;Nitric oxide;Xanthine oxidase;Tyrosinase;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.22, no.2, 2009³â, pp.145-151
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200916638024015)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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