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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.17, no.3, 2004³â, pp.283-288
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½ÃÈ£ÃßÃâ¹°ÀÌ °£Àå±â´É ȸº¹¿¡ ¹ÌÄ¡´Â ¿µÇâ
( Effect of Siho (Bupleurum falcatum L.) Extracts on Liver Function in $CCl_4$ Intoxicated rats ) |
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| ½ÃÈ£³»¿¡ Á¸ÀçÇÏ´Â °£Àå±â´ÉÁõÁø¿¡ È¿°úÀûÀÎ ±â´É¼º ¹°ÁúÀÇ ¼ÒÀ縦 Ž»öÇϱâ À§ÇÑ ±âÃÊ¿¬±¸ÀÇ ÀÏÂ÷½ÇÇèÀ¸·Î $CCl_4$¿¡ ÀÇÇØ °£ÀåÀ» ¼Õ»ó½ÃŲ ÈòÁã¿¡°Ô MeOH ½ÃÈ£ÃßÃâ¹°À» ¼öÁØÀ» ´Þ¸® ÇÏ¿© ±Þ¿©ÇÑ ÈÄ °£ ¼Õ»ó Ä¡À¯ ¹× ±â´Éȸº¹¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» 󸮱º °£¿¡ ºñ±³, °ËÅäÇß´Ù. ±× °á°ú, Ç÷Áß AFP¹× Total protein·®Àº ½ÃÈ£ÃßÃ⹰󸮿¡ ÀÇÇØ °¨¼ÒÇß´Ù ±×·¯³ª Ç÷Áß AlbuminÀÇ ³óµµ´Â ÀÏÁ¤ÇÑ °æÇâÀ» º¸¿©ÁÖÁö ¾Ê¾Ò´Ù. Ç÷Áß AST¿Í ALTÀÇ È°¼ºÄ¡´Â ½Ãȣó ¸® ±º¿¡¼ Ç϶ôÇÏ¿´´Ù. Ç÷Áß ALP¿Í LDHÀÇ È°¼ºÄ¡´Â ½Ãȣ÷°¡±º¿¡¼ °¨¼ÒÇß´Ù ±×·¯³ª ${gamma}$-G7ÀÇ È°¼ºÄ¡´Â 󸮱º°£¿¡ ÀÏÁ¤ÇÑ °æÇâÀ» ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. Ç÷Áß Total cholesterol°ú Triglyceride·®Àº Àü ó¸® ±º¿¡¼ À¯ÀÇÇÑ Â÷À̸¦ º¸¿© ÁÖÁö ¾Ê¾Ò´Ù. |
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| Effect of Siho (Bupleurum falcatum L.) extracts on liver function were investigated in CCl4 intoxicated rats. Plasma $alpha$-fetoprotein and total protein concentration showed a tendency to decrease in Siho extracts groups. However plasma albumin concentration showed no significantly different in all treatment groups. Activities of plasma asparate aminotransferase and alanine aminotransferase in Siho extracts groups showed a lower values than control group. Alkan phosphatase and lactate dehydrogenase activities showed a tendency to decrease in Siho extracts groups. However ${gamma}$-glutamyl transferase activity showed no significantly different in all treatment groups. Concentration of plasma triglyceride and total cholesterol showed no significantly different in all treatment groups. |
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| Ű¿öµå |
| ALT;AST;$alpha$-fetoprotein;liver function;Siho (Bupleurumfalcatum L.); |
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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.17, no.3, 2004³â, pp.283-288
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200411922971615)
¾ð¾î : Çѱ¹¾î |
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| ³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø |
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