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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.18, no.2, 2005³â, pp.343-350
¹Ì³ª¸® ÁóÀÌ °ú»êÈ­ ÁöÁú°ú ¾ËÄÚ¿ÃÀ» Åõ¿©ÇÑ ÈòÁãÀÇ Ã¼ÁöÁú ±¸¼º, °£Àå±â´É ¹× Ç×»êÈ­´É¿¡ ¹ÌÄ¡´Â ¿µÇâ
( Effects of Oenanthe javanica Sap on Lipid Composition, Liver Function and Oxidative Capacity in Oxidized Fat and Ethanol Fed Rats )
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¹Ì³ª¸®ÁóÀÌ °ú»êÈ­ÁöÁú°ú ¾ËÄÚ¿ÃÀ» ±Þ¿©ÇÑ ÈòÁãÀÇ ÁöÁú±¸¼º, °£Àå±â´É°ú Ç×»êÈ­´É¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» °ËÅäÇß´Ù. Ç÷Àå ÃÑÄÝ·¹½ºÅ×·Ñ·®Àº °ú»êÈ­ÁöÁú°ú ¾ËÄÚ¿ÃÀ» ±Þ¿©ÇÑ Ã³¸®±º ¸ðµÎ°¡ Á¤»ó±ºº¸´Ù Áõ°¡ÇÏ¿´´Ù. ±×·¯³ª ¹Ì³ª¸®Áó 󸮱ºµéÀº ´ëÁ¶±ºº¸´Ù ³·¾Ò´Ù. Ç÷ÀåHDL-cholesterol·®Àº ¹Ì³ª¸®Áó 󸮱ºµéÀÌ ´ëÁ¶±º¿¡ ºñÇÏ¿© ³ôÀº °ªÀ» ³ªÅ¸³ÂÀ¸¸ç, Á¤»ó±º°ú À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. Ç÷Àå Triglyceride·®Àº °ú»êÈ­ÁöÁú°ú ¾ËÄÚ¿ÃÀ» ±Þ¿©ÇÑ Ã³¸®±º ¸ðµÎ°¡ Á¤»ó±º º¸´Ù Áõ°¡ÇÏ¿´À¸³ª, ¹Ì³ª¸®ÁóÀ» ó¸®ÇÑ ±ºÀÌ ´ëÁ¶±º º¸´Ù ³·Àº °ªÀ» º¸¿©, Ç϶ôÇÏ´Â °æÇâÀ» º¸¿´´Ù. °£ÀåÀÇ ÃÑÄÝ·¹½ºÅ×·Ñ·® ¹× Triglceride·®Àº ´ëÁ¶±ºÀÌ °¡Àå ³ôÀº °ªÀ» ³ªÅ¸³»¾úÀ¸¸ç, Á¤»ó±º°ú ¹Ì³ª¸®Áó 󸮱º°£¿¡´Â À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. Ç÷Àå ¹× °£ÀåÀÇ TBARS·®Àº Á¤»ó±º°ú ¹Ì³ª¸®Áó 󸮱ºÀº À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾ÒÀ¸¸ç, ´ëÁ¶±º º¸´Ù ³·Àº ¼öÄ¡¸¦ º¸¿´´Ù. Ç÷Àå GOT ¹× GPTÀÇ È°¼ºÄ¡´Â °ú»êÈ­ÁöÁú°ú ¾ËÄÚ¿ÃÀÇ ±Þ¿©¿¡ ÀÇÇØ Áõ°¡ÇÏ¿´À¸³ª, ¹Ì³ª¸®Áó 󸮿¡ ÀÇÇØ Ç϶ôÇß´Ù(P<0.05). °£Àå GSH-Px, SOD ¹× CATȰ¼ºÄ¡´Â ¹Ì³ª¸®Áó 󸮿¡ ÀÇÇØ Áõ°¡ÇÏ¿´´Ù.
Effects of Oenanthe javanica Sap on lipid composition, liver function and oxidative capacity were investigated in rats fed oxidized fat and ethanol. Twenty male Sprague-Dawley rats weighing $183.49;{pm};2.47g$ were distributed into four groups according to body weight and raised seven weeks with basal diet (normal group), basal diet, $10%$ oxidized fat and $50%$ ethanol (control group), basal diet, $10%$ oxidized fat, $50%$ ethanol and 1 ml Oenanthe javanica Sap (1 ml Oenanthe javanica Sap group) and basal diet, $10%$ oxidized fat, $50%$ ethanol and 1.5 ml Oenanthe javanica Sap (1.5 ml Oenanthe javanica Sap group), Total cholesterol and triglyceride in plasma showed a tendency to decrease in Oenanthe javanica Sap groups. However HDL-cholesterol in plasma showed a high values in Oenanthe javanica Sap groups and showed no significant difference to normal group. The values of total cholesterol and triglyceride in liver showed no significant difference in Oenanthe javanica Sap groups and normal group. The values of thiobarbituric acid in plasma and liver were lowered in the Oenanthe javanica Sap groups with no significance. Plasma GOT and GPT activity showed a tendence to decrease in Oenanthe javanica Sap groups. The values of GSH-Px, SOD and CAT activity showed a tendence to increase in the Oenanthe javanica Sap groups.
 
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Oenanthe javanica Sap;cholesterol;triglyceride;thiobarbituric acid;GSH-Px;SOD;CAT;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.18, no.2, 2005³â, pp.343-350
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200504704040738)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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