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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.19, no.5, 2006³â, pp.563-572
Rubus¼Ó ½Ä¹°¿¡ Á¸ÀçÇÏ´Â $19{alpha}-Hydroxyursane-type$ TriterpenoidÀÇ Æ¯¼º°ú ÀÌ¿ë
( Chemical Characterization and Utilization of $19{alpha}-Hydroxyursane-type$ Triterpenoids in Rubus species )
Á¤ÇöÁÖ;³²Á¤È¯;ÀÓ»óö;±è¿ø¹è;¹ÚÈñÁØ; »óÁö´ëÇб³ ÀÚ¿ø½Ä¹°Çаú;»óÁö´ëÇб³ ÀÚ¿ø½Ä¹°Çаú;»óÁö´ëÇб³ ÀÚ¿ø½Ä¹°Çаú;³óÃÌÁøÈïû °í·ÉÁö³ó¾÷¿¬±¸¼Ò;»óÁö´ëÇб³ ÀÚ¿ø½Ä¹°Çаú;
 
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The plant Rubus species (Rosaceae) mainly contains $19{alpha}-hydroxyurane-type$ triterpenoids $(19{alpha}-HUT)$ as bioactive components. Available functional food includes blackberry (the fruit of thornless Rubus sp.), red raspberry (R. idaeus) and black raspberry (R. occidentalis). However, the fruit of R. coreanus, which is used in Korea as a functional food, substitutes black raspberry. Rubi Fructus, which has been traditionally used as an oriental medicinal drug, designates only unripe fruit of R. coreanus but not its ripe fruit which indicates that it needs high content of $19{alpha}-HUT$ as a crude drug. Throughout our experiment, we found that ripe fruits contain very little amount of $19{alpha}-HUT$ when compared to unripe fruits. In addition, various and rich $19{alpha}-HUT$ has been reported from Rubus species. The most common structure of $19{alpha}-HUT$ of Rubus species, euscaphic acid or tormentic acid with $3{alpha}-OH$ or $3{eta}-OH$, respectively, can be glycosylated or oxidized to produce a number of $19{alpha}-HUTs $as euscaphic acid and tormentic acid derivatives and even esterified to form dimeric triterpenoids. In this review, the bioactivity and biosynthetic pathway and chemical characterization of $19{alpha}-HUTs$ found in Rubus species are discussed.
 
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Rubus;Rosaceae;Triterpenoid;Blackberry;$19{alpha}-hydroxyurane-type$;Tormentic acid;Euscaphic acid;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.19, no.5, 2006³â, pp.563-572
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200603043152333)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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