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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.19, no.5, 2006³â, pp.602-605
û°¢ÀÇ ÁöÁú°­ÇÏ ¹× Ç×»êÈ­È¿°ú
( Effects of Cheunggak (Codium fragile) on lowering Lipid and Antioxidant )
ÀÌÀº; »óÁö´ëÇб³ »ý¸íÀÚ¿ø°úÇдëÇÐ;
 
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û°¢ ÃßÃâ¾×ÀÌ ºñ¸¸À» À¯µµÇÑ ÈòÁãÀÇ ÁöÁú°­ÇÏ ¹× Ç×»êÈ­È¿°ú¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» °ËÅäÇß´Ù. °¢ 󸮱º º° À¯¸®Áö¹æ»êÀÇ ³óµµ´Â û°¢ 󸮱º ¸ðµÎ°¡ ´ëÁ¶±ºº¸´Ù ³·Àº °ªÀ» º¸¿´´Ù. Triglyceride ·®Àº ´ëÁ¶±º°ú ºñ±³ÇÏ¿© û°¢ 󸮱ºÀÌ À¯ÀÇÇÏ°Ô ³·Àº °ªÀ» º¸¿´À¸¸ç, û°¢ ÷°¡·®ÀÌ Áõ°¡ÇÔ¿¡ µû¶ó Ç϶ôÇß´Ù. Ç÷¾× ³» total cholesterol ¹× LDL-cholesterol³óµµ´Â û°¢ 󸮱º ¸ðµÎ¿¡¼­ °¨¼ÒÇÏ´Â °æÇâÀ» º¸¿´´Ù. ±×·¯³ª HDL-cholesterol·®Àº ´ëÁ¶±ºÀ» ºñ·ÔÇÏ¿© Àü 󸮱º¿¡¼­ À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. °£Àå ³» total cholesterol°ú triglyceride·®Àº û°¢ 󸮱º ¸ðµÎ¿¡¼­ Ç϶ôÇÏ´Â °æÇâÀ» º¸¿© Á¤»ó±ºÀÇ ¼öÁØÀ» À¯ÁöÇÏ¿´´Ù. Ç÷Àå ¹× °£ÀåÀÇ TBARS ³óµµ´Â û°¢Ã³¸®±º ¸ðµÎ°¡ Ç϶ôÇÏ´Â °æÇâÀ» º¸¿´À¸¸ç, Á¤»ó±ºÀÇ ¼öÁذú À¯»çÇÑ ¼öÄ¡¸¦ ³ªÅ¸³»¾ú´Ù. GSH-PxÀÇ È°¼ºÄ¡´Â û°¢ 󸮷®ÀÌ Áõ°¡ÇÔ¿¡ µû¶ó Áõ°¡ÇÏ´Â °æÇâÀ» º¸¿©, 200mg/kg 󸮱º¿¡¼­´Â Á¤»ó±ºÀÇ È°¼ºÄ¡¿Í À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. ±×·¯³ª SOD Ȱ¼ºÄ¡´Â û°¢Ã³¸®¿¡ °ü°è¾øÀÌ Á¤»ó±ºÀ» ºñ·ÔÇÑ Àü 󸮱º¿¡¼­ À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù. ¶ÇÇÑ CATÀÇ È°¼ºÄ¡´Â û°¢ 󸮱º¿¡¼­ ´Ù¼Ò Áõ°¡ÇÏ´Â °æÇâÀ» º¸¿´À¸³ª, ´ëÁ¶±º°ú À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö´Â ¾Ê¾Ò´Ù.
Effects of Codium fragile ext. on lipid lowering and antioxidant activities were investigated in hyperlipidemic rat. Concentration of FFA and triglyceride in plasma showed a tendency to decrease in Codium fragile ext. groups. Concentration of plasma total cholesterol and LDL-cholesterol in Codium fragile ext. groupsshowed a low values than those of control group. However concentration of HDL-cholesterol showed no significant difference in all treatment groups. Concentration of liver total cholesterol and triglyceride showed a tendence to decrease in Codium fragile ext. groups. Concentration of plasma and liver TBARS showed a low values in Codium fragile ext. groups. The values of GSH-Px activity showed a tendency to increase in the Codium fragile ext. groups, However the values of SOD and CAT activity showed no significant difference in all treatment groups.
 
Ű¿öµå
Codium fragile;Cholesterol;Triglyceride;Thiobarbituric acid;GSH-Px;SOD;CAT;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.19, no.5, 2006³â, pp.602-605
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200603043152269)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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