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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.20, no.6, 2007³â, pp.499-503

( In Vitro Assay on Antioxidant Activity and Cytotoxicity of Methanol Extracts from Young Sprouts of Several Korean Salad Plants )
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Antioxidant activity, total phenolics level and cytotoxicity of the methanol extracts from the young sprouts of 5 Korean woody salad plants were determined. Methanol extracts of Kalopanax pictus had the highest DPPH radical scavenging activity, with an $IC_{50}$ value of 23.5mg $100g^{-1}$, and followed by Valeriana fauriei(43.1mg $100g^{-1}$), and Morus alba(>100mg $100g^{-1}$). Total phenolic content showed the highest amount in methanol extracts from Kalopanax pictus(23.7mg $100g^{-1}$), and followed by Valeriana fauriei(22.7mg $100g^{-1}$), Aralia elata(16.8mg $100g^{-1}$) and Morus alba(14.2mg $100g^{-1}$). In a MTT assay, methanol extracts of Aralia elata with $IC_{50}$ values of 151.0 and $140.7{mu}g;mL^{-1}$ showed the most potent cytotoxicity on Calu-6 and MCF-7, respectively. On the other hand, methanol extracts of Kalopanax pictus($IC_{50}=96.5{mu}g;mL^{-1}$) showed the highest activity against HCT-116, and followed by those of Aralia elata($123.3{mu}g;mL^{-1}$), and Actinidia arguta($162.0{mu}g;mL^{-1}$). Total phenolic content of the tested plant extracts was correlated with the DPPH radical scavenging activity, suggesting the phenolic compounds may contribute to the antioxidant properties of Korean salad plants.
 
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Korean salad plants;DPPH radical scavenging activity;Total phenolic content;Cytotoxicity;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.20, no.6, 2007³â, pp.499-503
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ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200706414482222)
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