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한국자원식물학회 / v.19, no.6, 2006년, pp.655-659 
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( Isolation of Dineolignans, Saucernetin-7 and -8, with Nitric Oxide Inhibitory Activity and NMR assignment from Saururus chinensis ) |
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| 초 록 |
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| Two dineolignans (1,2) with nitric oxide inhibitory activities were isolated from Saururus chinensis (Saururaceae) using silica gel column chromatography. Although the structures, saucernetin-7 (1) and -8 (2), have been already reported, NMR assignment of the two compounds was completed aided by 2D-NMR spectroscopy including $^1H-^1H$ COSY, $^1H-^{13}C$ COSY, HMBC and NOESY NMR spectra. Compounds 1 and 2 exhibited significant nitride oxide inhibitory activity in LPS-induced RAW 264.7 cells with $IC_{50}$ values of $11.3{mu}M;and;7.1{mu}M$, respectively. |
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| 키워드 |
| Saururus chinensis;Saururaceae;Dineolignan;Lignan;Saucernetin;NMR assignment; |
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한국자원식물학회지 / v.19, no.6, 2006년, pp.655-659
한국자원식물학회
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200606141806384)
언어 : 영어 |
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| 논문 제공 : KISTI 한국과학기술정보연구원 |
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