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Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ / v.13, no.1, 2000³â, pp.54-60
¹Ì³ª¸®ÁóÀÌ °íÁö¹æ½ÄÀ̸¦ ±Þ¿©ÇÑ ÈòÁãÀÇ Ç÷ûÁöÁú±¸¼º¿¡ ¹ÌÄ¡´Â ¿µÇâ
( Effect of Oenanthe javanica Sap on Plasma Lipid Composition in Rats with High-Fat Diet )
ÃÖ¹«¿µ;ÃÖÀºÁ¤;ÀÌÀº;¹ÚÈñÁØ; »óÁö´ëÇб³ ½Äǰ¿µ¾çÇаú;»óÁö´ëÇб³ ½Äǰ¿µ¾çÇаú;»óÁö´ëÇб³ ÀÀ¿ëµ¿¹°°úÇкÎ;»óÁö´ëÇб³ ÀÀ¿ë½Ä¹°°úÇкÎ;
 
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¹Ì³ª¸®Áó Åõ¿©°¡ °íÁö¹æ½ÄÀ̸¦ ±Þ¿©ÇÑ ÈòÁãÀÇ Ç÷Àå°ú ÁöÁú°ú»êÈ­¿¡ ¹ÌÄ¡´Â ¿µÇâ¿¡ ´ëÇÏ¿© °ËÅäÇÏ¿´´Ù. Sprague-Dawely°èÀÇ ÈºÁ㸦 I(Á¤»ó±º)°ú II(´ëÁ¶±º:°íÁö¹æ½ÄÀ̱޿©±º), ±×¸®°í ¹Ì³ª¸®ÁóÀÇ Ã³¸®¼öÁØ¿¡ µû¶ó III(°íÁö¹æ½ÄÀ̱޿©±º+¹Ì³ª¸®Áó(1.0 ml) °ú IV(°íÁö¹æ½ÄÀ̱޿©±º+¹Ì³ª¸®Áó(1.5 ml)ÀÇ 4±ºÀ¸·Î ³ª´©¾î 7ÁÖ°£ »çÀ°ÇÏ¿´´Ù. ½ÇÇèÁ¾·áÀÏÀÇ Ã¼ÁßÀº °íÁö¹æ½ÄÀÌ ±Þ¿©·Î ¸ðµÎ°¡ Á¤»ó±ºº¸´Ù ³ôÀº ¼öÄ¡¸¦ º¸¿´´Ù(p>0.05). ±×·¯³ª ´ëÁ¶±º°ú ¹Ì³ª¸®Áó±º °£¿¡´Â ¹Ì³ª¸®Áó±ºÀÌ ´Ù¼Ò °¨¼ÒÇÏ´Â °æÇâÀ̾úÀ¸³ª À¯ÀÇÀûÀÎ Â÷ÀÌ´Â ¾ø¾ú´Ù(p>0.05). ½ÄÀ̼·Ãë·® ¹× È¿À²Àº °¢ 󸮱º°£¿¡ À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾Ò´Ù (p>0.05). Total-cholesterolµµ ¹Ì³ª¸®Áó Åõ¿©¿¡ ÀÇÇØ °¨¼ÒÇÏ´Â °æÇâÀ» ³ªÅ¸³»¾úÀ¸³ª À¯ÀÇÀûÀÎ Â÷ÀÌ´Â ¾ø¾ú´Ù(p>0.05), HDL-cholesterolÀº ¹Ì³ª¸®Áó(1.0 ml) ±Þ¿©±ºÀÌ ´ëÁ¶±º¿¡ ºñÇÏ¿© °¨¼ÒÇÏ¿´´Ù. GPT´Â 󸮱º°£¿¡ À¯ÀÇÂ÷°¡ ¾ø¾úÀ¸³ª GOTȰ¼ºÀº 󸮱ºÀÌ ´ëÁ¶±º¿¡ ºñÇØ °¨¼ÒÇÏ´Â °æÇâÀ» ³ªÅ¸³»¾ú´Ù. Ç×»êÈ­È¿¼ÒÀÎ glutathione peroxidaseÀÇ È°¼ºÀº 󸮱º °£¿¡ À¯ÀÇÇÑ Â÷ÀÌ´Â ¾ø¾ú´Ù(p>0.05). Lipid peroxide´Â °íÁö¹æ½ÄÀÌ ±Þ¿©±º¿¡¼­ Áõ°¡ÇÏ¿´À¸³ª(p>0.05), ¹Ì³ª¸®ÁóÀÇ Åõ¿©´Â lipid peroxide¸¦ °¨¼Ò½ÃŰÁö ¸øÇÏ¿´´Ù.
To investigate the effects of Oenanthe javanica sap (OJS) on plasma lipid composition, several biochemical parameters such as total cholesterol, HDL-cholesterol, triglyceride, GOT, GPT and malodialdehyde were compared in the four groups as follows: a normal group with basal diet, a control group with high-fat diet, a treatment group with high-fat diet and OJS 1 ml/kg, and the other treatment group with high-fat diet and OJS 1.5 mg/kg. In addition, the body weight change, food intake and food efficiency ratios were measured. In this study, treatment groups decreased plasma total cholesterol levels.
 
Ű¿öµå
Oenanthe javanica;sap;lipid peroxidation;glutathione peroxidase;
 
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸÁö / v.13, no.1, 2000³â, pp.54-60
Çѱ¹ÀÚ¿ø½Ä¹°ÇÐȸ
ISSN : 1226-3591
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200011921402570)
¾ð¾î : Çѱ¹¾î
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