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Çѱ¹ÇÏõȣ¼öÇÐȸ / v.36, no.2, 2003³â, pp.85-97
¾î·ù¸¦ ÀÌ¿ëÇÑ ³»ºÐºñ°è Àå¾Ö¹°Áú °ËÃâ ¹× Biomarker·Î¼­ VitellogeninÀÇ ÀÌ¿ë
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À±¼®ÁÖ;±èÀÏÂù;À±¿ë´Þ;ÀÌÀ缺; ÇѾç´ëÇб³;ÇѾç´ëÇб³;ÇѾç´ëÇб³;ÇѾç´ëÇб³;
 
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¾î·ù vitellogeninÀº ³­È²Àü±¸Ã¼·Î ³­Çü¼º°úÁ¤µ¿¾È¿¡ estradiolÀÇ Ã¼³» ¼øÈ¯¿¡ ÀÇÇØ ¾ÏÄÆÀÇ °£¿¡¼­ »ý»êµÇ¸ç alkylphenol·ù¿Í °°Àº ºñÀ̿¼º °è¸éȰ¼ºÁ¦ µîÀÇ ³»ºÐºñ°è Àå¾Ö¹°Áú¿¡ ÀÇÇØ ¼öÄÆ¿¡¼­µµ »ý»êµÈ´Ù. ¹° ȯ°æÀÇ ÁÖ¿ä »ý¹°Á¾ÀÎ ¾î·ù´Â ³»ºÐºñ°èÀå¾Ö¹°Áú¿¡ ÀÇÇØ ¾ÏÄÆ¿¡¼­´Â ¹ø½Ä·ü ÀúÇÏ¿Í ÇÔ²² ¼öÄÆ¿¡¼­´Â Á¤¼ÒÀÇ Ãà¼Ò ¹× ÀÌ¿¡ µû¸¥ ¾ÏÄÆÈ­°¡ °üÂûµÈ´Ù. ƯÈ÷ ¼öÄÆ¿¡¼­ ³»ºÐºñ°è Àå¾Ö¹°Áú¿¡ ÀÇÇØ À¯µµµÈ vitellogeninÀÇ »ý¼ºÀ» ÀÌ¿ëÇÏ¿© ȯ°æ¿À¿°¿¡ ÀÇÇØ À¯µµµÈ »ý¹°Ã¼ÀÇ À¯ÀüÀÚ ¹ßÇö º¯È­ »Ó¸¸ ¾Æ´Ï¶ó À̸¦ Åä´ë·Î ƯÁ¤Áö¿ªÀÇ È¯°æ¿À¿°À» ¸ð´ÏÅ͸µÇÒ ¼ö ÀÖ´Ù. º» ³í¹®¿¡¼­´Â ¾î·ùÀÇ vitellogenin¸¦ ÀÌ¿ëÇÏ¿© ¼öȯ°æÀÇ ³»ºÐºñ°èÀå¾Ö¹°ÁúÀÇ °ËÃâ°ú ȯ°æ¿À¿° ¸ð´ÏÅ͸µÀ» À§ÇÑ biomarker·Î¼­ÀÇ À¯¿ë¼ºÀ» °ËÅäÇÏ¿´´Ù.
Fish vitellogenin produces in female liver during oogenesis trough estradiol cycle, and produced even in male liver by endocrine-disrupting chemiclas (EDCs) such as alkyphenols. The resulting effects of EDCs lead to the low fecundity of female and the feminization (eg. shrinkage of testis) in male. Especially, the production of vitellogenin in male indicates the environmental contamination of EDCs, resulting in the modulation of gene expression profiles and the monitoring of environmental contamination at specific area. In this paper, we suggest that fish vitellogenin is useful for biomonitoring for environmental contamination and would be substantially useful as a biomarker for a detection of EDCs in aquatic environmemt.
 
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Endocrine disruptor;EDC;Fish;Vitellogenin;Biomarker;
 
Çѱ¹ÇÏõȣ¼öÇÐȸÁö / v.36, no.2, 2003³â, pp.85-97
Çѱ¹ÇÏõȣ¼öÇÐȸ
ISSN : 1976-8087
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200310103401474)
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