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Çѱ¹ÇÏõȣ¼öÇÐȸ / v.37, no.3, 2004³â, pp.313-318
Di-2-ethylhexyl Phthalate (DEHP)¿¡ ³ëÃâµÈ µ¿ÀÚ°³, Pseudobagrus fulvidracoÀÇ Ç÷¾×Àû
( Di-2-ethylhexyl Phthalate Induced Haematological Effects in Bagrid Catfish, Pseudobagrus fulvidraco After Short Term Exposure )
ÁöÁ¤ÈÆ;±ÝÀ¯È­;°­ÁÖÂù; ºÎ°æ´ëÇб³ ¼ö»ê°úÇבּ¸¼Ò;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÇаú;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÇаú;
 
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Di-2-ethylhexyl Phthalate (DEHP)´Â ³»ºÐºñÀå¾Ö¹°Áú·Î ºÐ·ùµÇ¾î ÀÖ´Â ÇÃ¶ó½ºÆ½ °¡¼ÒÁ¦·Î¼­ in vitro¿¡¼­ Ç÷±¸¼¼Æ÷¸·¿¡ ¿µÇâÀ» ÁÖ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. º» ¿¬±¸´Â µ¿ÀÚ°³, Pseudobagrus fulvidraco¸¦ ´ë»óÀ¸·Î DEHP ±Þ¼º ³ëÃâ¿¡ µû¸¥ Ç÷¾×ÇÐÀû ¿µÇâÀ» ÆÄ¾ÇÇϱâÀ§ÇÏ¿© ¾îüÁß ´ç 300 ¹× 1,000 mgÀÇ DEHP¸¦ º¹°­ÁÖ»çÇÏ¿´´Ù. DEHP (1,000 mg b.w. $^{-1}$¿¡ ³ëÃâµÈ µ¿ÀÚ°³´Â ÀûÇ÷±¸¼ö¿Í Ç÷»ö¼Ò ³óµµ ¹× ÀûÇ÷±¸ ¿ëÀûÀÌ °¨¼ÒÇÏ´Â °æÇâÀ» ³ªÅ¸³»¾ú´Ù. ¶ÇÇÑ, Ç÷û ³» À¯±â¼ººÐÀÎ ÃѴܹéÁú·®, ÄÝ·¹½ºÅ׸¦ ¼öÄ¡´Â 300 ¹× 1,000 mg Áֻ籸¿¡¼­ À¯ÀÇÀûÀ¸·Î °¨¼ÒÇÏ¿´À¸¸ç Áö¹æ»êÀÇ ³óµµ´Â 1,000 mg Áֻ籸¿¡¼­ ´ëÁ¶±¸¿Í ºñ±³ÇÏ¿© À¯ÀÇÀûÀ¸·Î °¨¼ÒÇÏ¿´´Ù. Ç÷û ¹«±â¼ººÐÀÎ Ä®½·³óµµ¿Í Ç÷¾× »ïÅõ¾Ð ³óµµ´Â 1,000 mg DEHP ³ëÃⱸ¿¡¼­ À¯ÀÇÀûÀÎ °¨¼Ò°¡ °üÂûµÇ¾ú´Ù.
Di-2-ethylhexyl phthalate (DEHP) is a widely used plasticizer known to be a suspected xenoestrogen and a causative agent of oxidative damage to the RBC cell membrane ir vitro. We evaluated the toxic effects of a scarcely documented aquatic environmental pollutant, DEHP, on selected haematological endpoints in the bagrid catfish, Pseudobagrus fulvidraco. Bagrid catfish were exposed to DEHP (300, 1,000 mg DEHP kg body weight$^{-1}$) through thrice intraperitoneal injection and effects were assessed in blood of the exposed organisms. Haematological property, serum organic and inorganic chemistry were monitored in blood of Bagrid catfish. DEHP exposed-fish showed erythropenia; low hematocrit (Ht) and hemoglobin (Hb) content and red blood cell count showed a significantly higher than in that of the control group. The treatment group showed a significantly lower concentration of serum total protein, cholesterol and triglyceride compared with those in the control group. The value of calcium and osmolality were significantly decreased in the DEHP treatment group, compared with the control group.
 
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Di-2-ethylhexyl Phthalate (DEHP);haematological property;Pseudobagrus fulvidraco;serum chemistry;toxic responses;
 
Çѱ¹ÇÏõȣ¼öÇÐȸÁö / v.37, no.3, 2004³â, pp.313-318
Çѱ¹ÇÏõȣ¼öÇÐȸ
ISSN : 1976-8087
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200418317183145)
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³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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