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Çѱ¹È¯°æ»ý¹°ÇÐȸ / v.21, no.1, 2003³â, pp.1-7
¼ö¼­ ȯ°æµ¶¼º Æò°¡¿Í ¾î·ù Cytochrome P450 1A (CYP1A) À¯ÀüÀÚ
( Assessment of Toxic Effects in Aquatic Environment and the Fish Cytochrome P450 1A(CYP1A) Gene )
À±¼®ÁÖ;±èÀÏÂù;À±¿ë´Þ;ÀÌÀ缺; ÇѾç´ëÇб³ ÀÚ¿¬°úÇבּ¸¼Ò, ÇѾç´ëÇб³ ´ëÇпø ȯ°æ°úÇаú;ÇѾç´ëÇб³ Àǰú´ëÇÐ »ýÈ­Çб³½Ç;ÇѾç´ëÇб³ ÀÚ¿¬°úÇдëÇÐ »ý¸í°úÇаú;ÇѾç´ëÇб³ ´ëÇпø ȯ°æ°úÇаú;
 
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CYP1A À¯ÀüÀÚ´Â cytochrome P450 ¾à¹°´ë»çÈ¿¼Ò¿¡ ¼ÓÇÏ¸ç ´ÙÀÌ¿Á½Å µîÀÇ ³»ºÐºñ°è Àå¾Ö¹°Áú¿¡ ÀÇÇØ ³óµµ ÀÇÁ¸ÀûÀ¸·Î À¯µµµÇ¾î ȯ°æ¿À¿°¹°Áú¿¡ ÀÇÇØ À¯µµµÇ´Â Ư¼ºÀ» ÀÌ¿ëÇÏ¿© ȯ°æ¿À¿°¹°Áú¿¡ ´ëÇØ ¹ÝÀÀÇÏ´Â »ý¹°Ã¼ÀÇ À¯ÀüÀÚ ¹ßÇö º¯È­»Ó¸¸ ¾Æ´Ï¶ó À̸¦ Åä´ë·Î ƯÁ¤Áö¿ªÀÇ È¯°æ¿À¿°¿¡ °üÇÑ Á¤º¸¸¦ ¾òÀ» ¼ö ÀÖ´Ù. º» ³í¹®¿¡¼­´Â ¼ö¼­È¯°æ¿À¿°°ú °ü·ÃÇÏ¿© CYP1AÀ¯ÀüÀÚÀÇ À¯¿ë¼ºÀ» ´Ù°¢µµ·Î ³íÀÇÇÏ¿´´Ù.
The CYP1A gene is one of Cytochrome P450 drug-metabolizing enzymes with dose-dependant manner of gene expression and is useful to get the information of alterations on gene expression upon environmental contaminants as well as the biomarker of environmental contamination at the specific places. In this report, we further discuss the usefulness of CYP1A gene in relation to aquatic environmental contamination at several aspects.
 
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Fish;CYP1A;Biomarker;
 
ȯ°æ»ý¹° / v.21, no.1, 2003³â, pp.1-7
Çѱ¹È¯°æ»ý¹°ÇÐȸ
ISSN : 1226-9999
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200311921575107)
¾ð¾î : Çѱ¹¾î
³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø
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