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Çѱ¹È¯°æ»ý¹°ÇÐȸ / v.22, no.3, 2004³â, pp.387-393
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»ç·á¸¦ ÅëÇÑ Benzo(a)pyrene ³ëÃâ¿¡ µû¸¥ Á¶ÇǺ¼¶ô, Sebastes schlegeliÀÇ »ýÈÇÐ ¹× Á¶Á÷º´¸®ÇÐÀû º¯È
( Biochemical and Histopathological Changes of Rockfish, Sebastes schlegeli by Dietary Benzo(a)pyrene ) |
| ¹Ú´ë±¹;±èÀç¿ø;ÁöÁ¤ÈÆ;¹Ú¼öÀÏ;°ÁÖÂù; ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÀÇÇаú;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÀÇÇаú;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÀÇÇаú;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÀÇÇаú;ºÎ°æ´ëÇб³ ¼ö»ê»ý¸íÀÇÇаú;
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| »ç·á¸¦ ÅëÇÑ benzo(a)pyreneÀÌ Á¶ÇǺ¼¶ô, Sebastes schlegeliÀÇ lipid peroxidation (LPO), superoxide dismutase(SOD)Ȱ¼º°ú °£ Á¶Á÷ÀÇ º´º¯ Çö»ó¿¡ ¹ÌÄ¡´Â ¿µÇâÀ» ¿¬±¸ÇϱâÀ§ÇØ 0 (´ëÁ¶±¸), 0.5, 1.0, 1.5, 2.0 mg $kg^{-1}$ ³óµµÀÇ »ç·á¸¦ Á¶Á¦ÇÏ¿© 30Àϰ£ ±ÞÀÌÇÏ¿´´Ù. LPO´Â 2.0mg kg$^{-1}$³óµµ±¸¿¡¼ Àü ½ÇÇè±â°£ µ¿¾È À¯ÀÇÀûÀ¸·Î Áõ°¡ÇÏ¿´°í, SOD Ȱ¼ºµµ 2.0 mg $kg^{-1}$ ³óµµ±¸¿¡¼ 30Àϰ¿¡ À¯ÀÇÀûÀ¸·Î Áõ°¡ÇÏ¿´´Ù. °£ Á¶Á÷ °Ë°æ½Ã 10Àϰ¿¡ 1.0mg $kg^{-1}$ ÀÌ»óÀÇ ³óµµ±¸¿¡¼ ¼¼Æ÷ºñ´ë°¡ ³ªÅ¸³µ°í, °°Àº ³óµµ¿¡¼ periodic acid-Schiff (PAS) ¿°»ö½Ã ¾ç¼ºÀ¸·Î ³ªÅ¸³ª´Â granuleÀÌ 30Àϰ¿¡ ³ªÅ¸³µ°í, 2.0mg $kg^{-1}$ ³óµµ±¸¿¡¼´Â 20ÀϰºÎÅÍ °üÂûµÇ¾ú´Ù. ±×¸®°í, 30Àϰ 2.0mg $kg^{-1}$ ³óµµ±¸ÀÇ ÀϺΠ¾îü¿¡¼´Â °£ ¼¼Æ÷ÀÇ ±«»ç°¡ °üÂûµÇ¾ú´Ù. |
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| Experiments were carried out to investigate the lipid peroxidation (LPO), superoxide dismutase (SOD) activity and histopathological change of hepatic tissue for rockfish, Sebastes schlegeli after feeding sub-chronic dietary Benzo(a)pyrene (BaP) in the concentration of 0 (control), 0.5, 1.0, 1.5, 2.0 mg $kg^{-1}$ dry food of diet for 30 days. In 2.0 mg $kg^{-1}$ dry food group, the significant increase of LPO was observed in all period, and SOD activity was incresed at 30 days significantly in the same concentration. In the histological investigation of liver, there was the swelling of hepatic cells at 10 days over the 1.0 mg $kg^{-1}$ dry food concentration. At 30 days Periodic acid-Schiff (PAS) positive granule was observed in the same group and at 20 days was observed in 2.0 mg $kg^{-1}$ dry food group. And there was necrosis of hepatic cell in some fish of 2.0 mg $kg^{-1}$ dry food group at 30 days. |
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| Ű¿öµå |
| Sebastes schlegeli;benzo(a)pyrene;lipid peroxidation;superoxide dismutase;histophathological change;dietary; |
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ȯ°æ»ý¹° / v.22, no.3, 2004³â, pp.387-393
Çѱ¹È¯°æ»ý¹°ÇÐȸ
ISSN : 1226-9999
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200412910473719)
¾ð¾î : Çѱ¹¾î |
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| ³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø |
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