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한국환경생물학회 / v.22, no.4, 2004년, pp.513-518 
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( Study on the Subacute Toxicity of Complex of Pine Needle Oil and Korean Medicinal Herbs against Rats ) |
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| 초 록 |
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| Pine needle oil and Korean medicinal herbs (KMH) are known as effective therapeutic agents on various blood vessel disease. We have already reported the ameliorative effect of complex of pine needle oil and Korean medicinal herbs against hyperlipidemia. But safety and non - toxicity of pine needle oil and Korean medicinal herbs to normal animal cells have not been studied clearly. In this study, we investigated whether pine needle oil and Korean medicinal herbs show side effects on rat or not. These materials were administered to rats, and subacute toxicity was examined by measuring the hematological values, CBC differentiation, biochemical levels of blood (TP, total protein; albumin; ALP, alkaline phosphotase; AST, aspatate aminotrans- ferase; ALT, alanine aminotransferase; T-Chol., total cholesterol; T-Bil., total bilirubin) and urine analysis, suggesting that the sample have no side effects and cytotoxicity. These results indicate that the complex of pine needle oil and Korean medicinal herbs may effective non- toxic, safety therapeutic agents on hepatocytes and hyperlipidemia. |
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| 키워드 |
| pine needle oil;Korean medicinal herb;subacute toxicity;animal cells; |
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환경생물 / v.22, no.4, 2004년, pp.513-518
한국환경생물학회
ISSN : 1226-9999
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200414714193870)
언어 : 영어 |
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| 논문 제공 : KISTI 한국과학기술정보연구원 |
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