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Çѱ¹È¯°æ»ý¹°ÇÐȸ / v.23, no.3, 2005³â, pp.275-280

( Expression Changes of Chironomus riparius Proteome reflecting Ecdysterone Inducible Genes and Mitogenome exposure to Bisphenol-A )
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Development of the fourth-instar larvae of Chironomus riparius has a sensitive to ecdysteroid hormones. The 2D/E gel analysis for polypeptide expression reflecting early-ecdysterone inducible gene has conducted the emerged female from larval phase exposure to bisphenol A (BPA). In the 2D/E gel 1108 protein spots were identified. The visualized protein spots allowed extraction of 17 protein spots differed more than 3 fold in BPA treated animals, which was approximately $1.6%$ of the total protein spots. However, polypeptide expression reflecting early-ecdysterone inducible gene didn't change after treatments. In addition, detection for the damages or changes in mitogenome level was observed. The conserved cytochrome oxidase I in DNA level affected exposure to BPA $(1{mu}gL^{-1})$ in this preliminary study.
 
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Chironomus riparius;cytochrome oxidase I;polypeptide expression;bisphenol A;
 
ȯ°æ»ý¹° / v.23, no.3, 2005³â, pp.275-280
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ISSN : 1226-9999
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200504840632376)
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