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Çѱ¹È¯°æ»ýÅÂÇÐȸ / v.18, no.3, 2004³â, pp.340-345
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PCB°¡ »ê°³±¸¸®ÀÇ ¹è¾Æ¹ß»ý¿¡ ¹ÌÄ¡´Â ¿µÇâ
( The Effects of PCB on the Embryonic Development of a Korean Frog, Rana dybowskii ) |
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| º» ¿¬±¸¿¡¼´Â FETAXÀÇ ¹æ¹ý¿¡ µû¶ó PCB(Aroclor)°¡ »ê°³±¸¸®ÀÇ ¹è¾Æ¹ß»ý¿¡ ¹ÌÄ¡´Â È¿°ú¸¦ Á¶»çÇÏ¿´´Ù. ¹è¾ÆÀÇ Ä¡»çÀ²°ú ±âÇü·üÀº probit ºÐ¼®¹ýÀ¸·Î Á¶»çÇÏ¿´´Ù. PCB¿¡ ÀÇÇÑ LC$_{50}$Àº 1.48ppbÀ» ³ªÅ¸³Â°í EC$_{50}$Àº 0.25ppb¸¦ ³ªÅ¸³ÂÀ¸¸ç TI´Â 5.7À» ³ªÅ¸³»¾î PCB´Â ³ôÀº Ä¡»çÀ²À» ³ªÅ¸³»´Â ÃÖ±âÇü¼º ¹°Áú·Î ÆÇ´ÜµÈ´Ù. ±âÇü¾ç»óÀº ¼öÆ÷Çü¼º ±âÇüÀÌ 0.1ppb¿¡¼ 62.0%, ²¿¸®±âÇüÀÌ 1ppb¿¡¼ 32.0%, profundÇüÀÇ ±âÇüÀÌ 5ppb¿¡¼ 68.0%¸¦ ³ªÅ¸³Â´Ù. PCB´Â ºñ±³Àû ³·Àº ³óµµÀÎ 1.0ppb¿¡¼ ¸Ó¸®¿¡¼ ²¿¸®±îÁöÀÇ ¼ºÀåÀ» ÀúÇØÇÏ´Â °á°ú¸¦ ³ªÅ¸³»¾î ÀÌ·¯ÇÑ ¹è¾ÆÀÇ ¼ºÀå¾ïÁ¦¿¡ ÀÇ ÇÑ Æò°¡´Â ȯ°æ¿À¿°¹°ÁúÀÇ µ¶¼ºÀ» Æò°¡ÇÏ´Â µ¥ ¹Î°¨ÇÑ ÁöÇ¥·Î »ç¿ëµÇ¾îÁú ¼ö ÀÖÀ» °ÍÀ¸·Î »ý°¢µÈ´Ù. °á·ÐÀûÀ¸·Î ÀÌ·¯ÇÑ °á°ú´Â PCB°¡ »ê°³±¸¸® ¹è¾Æ¹ß»ý°úÁ¤¿¡ ³ôÀº µ¶¼ºÀ» Áö´Ñ °ÍÀ» ³ªÅ¸³½´Ù. |
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| The embryotoxic effects of PCB (Aroclor 1248) on a Korean frog, Rana dybowskii was deter-mined by using the FETAX (Frog Embryo Teratogenesis Assay-Xenopus) protocol. The rates of mortality and malformed larvae were investigated by probit analysis. The results showed that PCB is highly embryolethal. From LC$_{50}$ of 1.48ppb and from EC$_{50}$ of 0.25ppb and TI of 5.7 were derived, which indicates PCB is to be considered a teratogenic compound. Specific malformations occurred in 62.0% as edema at the 0.1ppb, in 32.0% as tail deformations at the 1ppb, and in 68.0% as profound deformations at the 5ppb of PCB concentration which living embryos were exposed to. PCB suppressed the growth of head-tail length at a relatively low concentration (1.0ppb), and therefore growth inhibition as assessed by embryo length can be used as a sensitive indicator to evaluate the toxicity of pollutants in the environment. In conclusion, PCB must be considered highly embryotoxic to Rana dybowskii. |
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| ÃÖ±âÇü¼º;TERATOGENESIS; |
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Çѱ¹È¯°æ»ýÅÂÇÐȸÁö / v.18, no.3, 2004³â, pp.340-345
Çѱ¹È¯°æ»ýÅÂÇÐȸ
ISSN : 1229-3857
UCI : G100:I100-KOI(KISTI1.1003/JNL.JAKO200413842110889)
¾ð¾î : Çѱ¹¾î |
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| ³í¹® Á¦°ø : KISTI Çѱ¹°úÇбâ¼úÁ¤º¸¿¬±¸¿ø |
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